Got Brain Fog?

 

It’s like thinking through a dirty window of fuzziness and forgetfulness, and even simple things feel harder.

 

Why does it happen?

 

3 things can happen in your brain:

• Toxin buildup
  (plaque and dead cells) 
• Inflammation
  (blocking neural flow) 
• Poor oxygen use
  (sluggish energy and circulation)

These are damaging to brain cells.

It’s harder to think, remember and feel good.

 

How can I fix it?

 

You can feed your brain the right nutrients to:

• Scrape off plaque
• Calm inflammation
• Improve oxygen use and energy.

These nutrients help your brain think faster, feel better and stay agile.

We call this the “Crystal Clear Mind” combo.

 

What does it look like?

 

There are two parts to the formula, the Detox and the Rewind, start with one bottle of each:

We suggest start with a bottle of each and most people over 45 will want to carry on with 2 caps/day of REWIND as it supports better age maintenance. You can just bring the Detox back in when you are feeling ‘foggy’ or for flu / allergy season.

 

 

Testimonials?

 

It is the astounding things people started to tell us after they were taking the two products together that made us realise what a great combination it is!

 

“Able to stay focused and on task”

“It’s like a dentist scraped the plaque off my brain”

“Like thinking with a reconditioned engine”

“Thought I was feeling old age,
I didn’t realise you could undo that!”

“With REWIND I was thinking and feeling 10 years younger,
but when I added Spike Detox the clarity was just something else.”

“I have a crystal clear mind now”

Four Critical Ingredients:

 

• • • The Age Defying Fountain of Youth (NMN & NR)

  Supports brain’s energy production and DNA repair,
  Supports brain energy supply,
  Support sirtuin activation,
  (better thinking, memory making and focus)

  • • The Queen of Longevity (Quercetin)

  Supports removal of dead cell buildup,
  Supports toxin clearing, 
  Maintains healthy inflammation levels,
  Supports BDNF for stronger neurons and neuroplasticity
  (adaptability and new connections)

  • • The Versatile Defender (NAC)

  Supports antioxidant defences and neurotransmitter balance
  Supporting emotional wellbeing, and cognitive performance,
  (and mood and motivation)

  • • The Oxygen Manager (Black Cumin Seed)

  Supports healthy circulation and respiratory function,
  Helping the brain access oxygen it needs for..
  (clear energised thinking)

 

Note: More nerdy science references below.

THE ‘AGE DEFYING FOUNTAIN OF YOUTH’ (NMN & NR)

(found in REWIND)

Nicotinamide mononucleotide (NMN) and Nictonamide Riboside (NR) are two ingredients that increase levels of a vital enzyme called NAD+. Boosting NAD+ levels improves brain function by enhancing several processes that are essential for healthy neurons and cognition. Some of these processes are:

 

• • • DNA repair:

      NAD+ is required for the activity of enzymes called PARPs, which fix DNA damage caused by oxidative stress, inflammation, or other factors. ¹ DNA damage can impair the function and survival of brain cells, leading to neurodegeneration and cognitive decline. ²

  • • Energy metabolism:

      NAD+ is involved in the production of ATP, the main energy source for cells, especially in the mitochondria. ³ Mitochondria are the powerhouses of the cell, and they are abundant in neurons, which have high energy demands. Dysfunctional mitochondria can cause neuronal death and impair synaptic transmission, affecting learning and memory. ⁴

  • • Sirtuin activation:

      NAD+ is a cofactor for a family of enzymes called sirtuins, which regulate gene expression, inflammation, stress resistance, and cellular lifespan. ⁵ Sirtuins have been shown to protect neurons from oxidative stress, inflammation, and apoptosis, as well as to modulate synaptic plasticity, neurogenesis, and memory formation. ⁶

‘THE QUEEN OF LONGEVITY’ (QUERCETIN)

(found in Spike Detox)

Quercetin was first discovered by Albert Szent-Györgyi who discovered Vitamin C, and called Vitamin P ( for permeability) partly because it travels right inside your brain. It is thought to improve brain function by changing the way your brain cells communicate (modulating neurotransmitters) and how they adapt to new information (called ‘synaptic plasticity’). It may also prevent or delay the onset of Alzheimer’s and Parkinson’s diseases by reducing amyloid plaque formation and neurotoxicity. ⁷

• • • Clears senescent cells

      Aging is partly caused by cellular senescence, a buildup of cells that have stopped growing and dividing but remain in the body, causing inflammatory damage to neighboring cells and tissues.  An accumulation of senescent cells is thought to be a large part of the aging puzzle—and quercetin may be able to help clear them naturally, inspiring a new class of drugs called ‘senolytics’. ⁸

  
  

  • • Supports Cognition

      Quercetin is an anti-oxidant that enters the brain reducing oxidative stress and buildup of reactive oxygen species (ROS), linking the compound to improved brain health and cognition. ⁹

  
  

  • • Increases neuroplasticity

      Lastly, a study in mice showed that Quercetin increased the levels of three proteins that are involved with cognition—brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and postsynaptic density protein-95 (PSD95). This trio of compounds is essential for the growth, survival and maintenance of neurons and helps strengthen neuroplasticity—the brain’s ability to grow and adapt by forming new neural connections. ¹⁰

THE ‘VERSATILE DEFENDER’ (N-ACETYLCYSTEINE)

(found in Spike Detox)

N-acetylcysteine (NAC) replenishes the body’s powerhouse antioxidant glutathione, and regulates the brain’s thinking juice, the ‘spark’ neurotransmitter glutamate. NAC may have some impact benefits for mental clarity, such as:

• • Lowering stress.

    NAC can help reduce the damage caused by reactive oxygen species (ROS), which are molecules that can harm your cells and tissues when they are too high. ROS can also increase inflammation and oxidative stress, which can impair your brain function and mood. NAC, (like Quercetin) can help lower ROS levels and protect your brain from stress ¹¹

 

• • Enhancing memory and learning.

    NAC can help modulate glutamate levels in the brain, which are important for cognitive processes such as memory and learning. Glutamate is the main excitatory neurotransmitter in the brain, but too much or too little of it can cause problems. NAC can help balance glutamate levels and prevent excitotoxicity, which is a condition where excess glutamate damages the brain cells. ^{12 13}

 

• • Improving mood and motivation.

    NAC can also affect dopamine levels in the brain, which are involved in reward, motivation, and pleasure. Dopamine is another neurotransmitter that can be affected by glutamate and ROS. NAC can help increase dopamine levels and activity in the brain, which may improve mood and motivation. ¹⁴

THE ‘OXYGEN MANAGER’ (BLACK CUMIN SEED)

(found in Spike Detox)

Black Cumin Seed supports healthy brain function via cholinergic support, synaptic plasticity, and neuroprotection:

 

• • Cognitive performance and Memory.

    Supports cognitive performance and memory by maintaining acetylcholine levels and reducing oxidative stress ^15 16

 

 

• • Mood and mental clarity.

    Black Seed supports mood and mental clarity by promoting BDNF and balancing neurotransmitters.  ¹⁷

 

 

• • Attention and Recall.

    Black Seed supports attention and recall by enhancing hippocampal activity and spatial memory. ^{15  16}